Figure 2
Assessment of transferability of signature genes across platform using T-index scores. A total of 54 permutations were tested to assess cross-platform transferability of signature genes, which consisted of two platforms, three ACs, three approaches for generating CT lists and three classification algorithms. A T-index score was calculated for each permutation to evaluate the transferability. (a) Compares the T-index scores that were generated by the three ACs, while (b) compares the results that were achieved with the three classification algorithms. (c) Depicts the T-index scores that were obtained with the three approaches for generating CT sets across the two platforms. Both AC and methods to select the CTs had little effect on the transferability while a degree of variability was observed for different classification algorithms.
