Figure 5

Insulin-like growth factor-I (IGF-I) signaling pathways: change in gene expression over 1 month of recombinant human growth hormone (r-hGH) therapy in (a) growth hormone deficiency (GHD) and (b) Turner syndrome (TS), as defined by Ingenuity Knowledge Base. Red indicates overexpressed genes and green suppressed genes. Gene expression within the IGF-I signaling pathway differs between GHD and TS in both number and nature of genes modulated.