Table 3 CYP2D6 activity scores of compliant patients

From: Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer

 

Singapore (n=160)

Lebanon (n=77)

POSH (n=311)

Overall (n=548)

CYP2D6 activity scores

No. of patients

%

No. of patients

%

No. of patients

%

No. of patients

%

0.0

0

 

4

5.2

25

8.0

29

5.3

0.5

12

7.5

4

5.2

28

9.0

44

8.0

0.75

52

32.5

2

2.6

7

2.25

61

11.1

1.0

13

8.1

15

19.5

95

30.5

123

22.4

1.5

48

30.0

15

19.5

53

17.0

116

21.2

2.0

32

20.0

27

35.1

102

32.8

161

29.4

3.0

1

0.6

10

13.0

1

0.3

12

2.2

Unknown

2

1.2

    

2

0.4

  1. Abbreviation: POSH, Prospective study of Outcomes in Sporadic versus Hereditary breast cancer.