Figure 4
From: Computational discovery of transcription factors associated with drug response
(a) Dosage–response curves for the transcription factor (TF) NFIC across two drugs, docetaxel (left) and paclitaxel (right), and two cell lines, MDA-MB-231 and BTF549. Each plot shows significant increase in resistance to the drug upon knockdown of NFIC compared with normal response of the cells, using a two-tailed paired t-test. (b) Dosage–response curves for the TF ELF1 across two drugs, doxorubicin (left) and epirubicin (right), and two cell lines, MDA-MB-231 and BTF549. Each plot shows significant increase in resistance to the drug upon knockdown of NFIC compared with normal response of the cells, using a two-tailed paired t-test.
