Figure 1
From: Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines
Overview of the Pharmacogenomics Research Network (PGRN) RNA-seq project. (1) 389 ‘PGRN pharmacogenes’ were selected representing genes that have a key role in drug disposition. (2) RNA from multiple samples for human liver, heart, kidney, adipose tissue and lymphoblastoid cell lines was collected. (3) Complementary DNA libraries were prepared from these samples and sequenced using an Illumina HiSeq 2000. (4) Rigorous pre- and post- alignment quality control procedures were applied to the data. (5) Gene expression was quantified and splicing events identified for the PGRN pharmacogenes across samples and tissue types. This information is provided as a resource to the pharmacogenomics community.
