Figure 2
From: The global spectrum of protein-coding pharmacogenomic diversity
Pharmacogenomic variants with a high level of clinical annotation (that is, PharmGKB Level 1A/B). (a) Scatterplot of allele frequencies of clinically relevant variants in the different population groups. Variants in certain genes, such as CY2C19 and CYP4F2, displayed differences in allele frequencies between super-populations. (b) Violin plot of the number of clinically relevant pharmacogenomic variants carried per individual, grouped by population, and coloured by super-population. Ninety-seven percent of the individuals in the 1000 Genomes Project carried at least one such variant (median of 3).
