Figure 3
From: The global spectrum of protein-coding pharmacogenomic diversity
Pharmacogenes that carried high-confidence loss-of-function (LOF) variants as designated by LOFTEE. (a) The size of the points is proportional to the number of unique LOF variants in the gene, with the cumulative allele count per gene indicated. (b) Combined allele frequencies of LOF variants per gene in each of the global super-populations. Common LOF variants were frequently driven by one super-population.
