Articles in 2020

Poon, Y-Y et al. re-visit the effects of isoflurane on cardiovascular functions by measuring temporal changes in blood pressure, heart rate, cardiac performance, baroreflex-mediated sympathetic vasomotor tone, cardiac vagal baroreflex, functional connectivity within baroreflex neural circuits, carotid or cerebral blood flow, respiratory rate and blood gas in mice exposed to 1.5% (vol/vol) isoflurane.

Here, the authors present a new fear-conditioning paradigm in zebrafish using a robotic platform composed of three zebrafish replicas as a fear-eliciting stimulus.

Continuous motion monitoring sensitively predicts terminal endpoint in a mouse model of ovarian cancer; the use of motion metrics could reduce animal suffering and be valuable for drug efficacy testing.

In rats, forced running wheel exercise activates an adaptation of the antioxidant system response in skeletal muscle at speeds <16 m/min, whereas it induces oxidative stress at higher speeds in muscle, liver and serum.