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A large network of interconnected neurons serves as the basis of brain function and of behavior. Methodological advances have enabled the reconstruction of large-scale and even whole-brain connectomes of various organisms.
Identifying individual cells and tracking their movements over time are two critically important tasks in bioimage analysis. We discuss a fresh wave of tools that push these techniques toward peak performance.
Technological advances change not only what we can learn as scientists, but also how science is conducted. Here we explore how automation and outsourcing are affecting the act of doing science.
Beginning this month, Nature Methods is rolling out a new project aimed at strengthening peer review: a formal co-reviewing initiative to recognize early-career researcher contributions. We also discuss our introduction of a reporting checklist to improve the transparency and reproducibility of light microscopy studies.
Vibrational microscopy methods offer bond-selective imaging, revealing the rich chemical composition of biological samples. In this Focus issue, we celebrate the past, present and future of these technologies, with an emphasis on how they are poised to enhance discovery in the life sciences.
Basic science and methods development is essential to ensure that lifesaving advances and improvements to the human condition continue moving forward. Such research needs strong and sustained funding support from governments.
Proper methods reporting is crucial for transparency, but ensuring method reusability by other labs takes a bit of extra effort. Here we discuss best practices for reporting methods so that they can be reused.
