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Brief Communications in 2021

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  • An online and interactive G-protein coupled receptor (GPCR) structure analysis platform allows any researcher to analyze and visualize a plethora of structure–function relationships across the scales of atomic interactions to protein backbone rearrangements.

    • Albert J. Kooistra
    • Christian Munk
    • David E. Gloriam
    Brief Communication
  • The cryo-EM structure of DNA-assembled histone pairs Hβ-Hα and Hδ-Hγ from Marseillevirus, a nucleocytoplasmic large DNA virus, reveals that these proteins form viral nucleosomes with highly conserved features when compared to canonical eukaryotic nucleosomes.

    • Marco Igor Valencia-Sánchez
    • Stephen Abini-Agbomson
    • Karim-Jean Armache
    Brief Communication
  • The SARS-CoV-2 spike ectodomain is destabilized by cold temperature storage, an effect that can be reversed by incubation at 37 °C or by stabilizing its conformation in the ‘down’ state.

    • Robert J. Edwards
    • Katayoun Mansouri
    • Priyamvada Acharya
    Brief Communication

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