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Here, the authors develop a systematic approach (Dip3D) for unraveling diploid high-order genome interactions for low-heterozygosity genomes using Pore-C. Using Dip3D they obtain an almost complete diploid three-dimensional genome interaction map for a human genome.
Here the authors present deep quantitative glycoprofiling (DQGlyco), a method that enables high-throughput analysis of protein glycosylation dynamics. Using DQGlyco, they link gut microbiome composition to brain glycoproteins and provide insights into glycoform functionality and tissue specificity.
