The WD40 domain of ATG16L1 is thought to be involved in non-canonical autophagy. Here the authors screen peptide libraries and identify interactions between this domain and the IL-2Rγ and IL-10RB receptors, indicating endosomal regulation of cytokine signalling by non-canonical autophagy.
- Inmaculada Serramito-Gómez
- Emilio Boada-Romero
- Felipe X. Pimentel-Muiños