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Showing 1–2 of 2 results
Advanced filters: Author: Åsa Sivertsson Clear advanced filters

  • Five validation pillars have been proposed to verify the specificity of research antibodies. Here the authors screen 6,000 antibodies from the Human Protein Atlas with these methods to provide an antibody validation resource for providers and users.

    • Fredrik Edfors
    • Andreas Hober
    • Mathias Uhlen
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-10

  • A multilaboratory pilot project demonstrates that hybridoma and phage display technologies can be applied to produce high-affinity, high-specificity renewable antibodies to a set of 20 human SH2 domain proteins in a reasonable time frame, suggesting that a systematic, large-scale effort to generate renewable protein binders will be feasible.

    • Karen Colwill
    • Helena Persson
    • Susanne Gräslund
    Research
    Nature Methods
    Volume: 8, P: 551-558