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Small-molecule autocatalysis drives compartment growth, competition and reproduction

The coupling of autocatalysis to compartment growth and division is a key step in the origin of life. Now it has been shown that compartmentalizing the formose reaction in emulsion droplets leads to several crucial properties of living and evolving systems (growth, division, variation, competition, rudimentary heredity and selection).

Heng Lu
Alex Blokhuis
Andrew D. Griffiths
Research07 Aug 2023
Nature Chemistry

Volume: 16, P: 70-78
Large riverbed sediment flux sustained for a decade after an earthquake

Bedload can dominate river sediment flux after a major earthquake for a prolonged time period.

Gen K. Li
A. Joshua West
Michael P. Lamb
Research13 Aug 2025
Nature

Volume: 644, P: 398-403
Cancer metabolomic markers in urine: evidence, techniques and recommendations

Urinalysis has long been used as a tool for managing diseases, but 21st century techniques have enabled measurement of metabolomic urinary cancer biomarkers using NMR and mass spectrometry. In this Review, the authors discuss the current status of research developments and offer recommendations to help systematize future research in the field.

Sarah S. Dinges
Annika Hohm
Leo L. Cheng
Reviews15 May 2019
Nature Reviews Urology

Volume: 16, P: 339-362
Influenza A virus reassortment in mammals gives rise to genetically distinct within-host subpopulations

Virus reassortment drives genetic diversity and evolution and is governed by intra-host dynamics that are less well understood. Here, the authors characterise the within-host dynamics of influenza A virus reassortment in swine, ferrets and guinea pigs, considering their spatial distribution.

Ketaki Ganti
Anish Bagga
Anice C. Lowen
ResearchOpen Access11 Nov 2022
Nature Communications

Volume: 13, P: 1-13
Therapeutic safety implications of SARM1 active site inhibitors: subinhibitory concentrations cause neurodegeneration

Rebecca R. Leahey
Martin Weber
Flora I. Hinz
ResearchOpen Access25 Aug 2025
npj Drug Discovery

Volume: 2, P: 1-8
Metabolomics in the study of kidney diseases

Metabolomics—the nontargeted measurement of all metabolites produced by the body—holds promise for early diagnosis, increased choice of therapy and the identification of new metabolic pathways that could potentially be targeted in kidney disease. This Review discusses the techniques used in metabolomics and explores the limitations and future applications of this process.

Robert H. Weiss
Kyoungmi Kim
Reviews25 Oct 2011
Nature Reviews Nephrology

Volume: 8, P: 22-33
Potential biofluid markers and treatment targets for renal cell carcinoma

In this Review, Wettersten and Weiss discuss novel urinary and blood biomarkers and therapeutic targets for renal cell carcinoma, with the hope that dissemination of this information might lead to clinical utilization.

Hiromi I. Wettersten
Robert H. Weiss
Reviews02 Apr 2013
Nature Reviews Urology

Volume: 10, P: 336-344
Erratum: MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway

M A Macha
S Rachagani
S K Batra
Amendments and Corrections21 May 2015
Oncogene

Volume: 34, P: 2814
Improvement of Storage Medium for Cultured Human Retinal Pigment Epithelial Cells Using Factorial Design

L. Pasovic
T. P. Utheim
J. R. Eidet
ResearchOpen Access09 Apr 2018
Scientific Reports

Volume: 8, P: 1-17
Novel role of pancreatic differentiation 2 in facilitating self-renewal and drug resistance of pancreatic cancer stem cells

A P Vaz
M P Ponnusamy
S K Batra
ResearchOpen Access08 Jul 2014
British Journal of Cancer

Volume: 111, P: 486-496
Cell-free DNA as a diagnostic analyte for molecular diagnosis of vascular malformations

Kaitlyn Zenner
Dana M. Jensen
James T. Bennett
Research04 Sept 2020
Genetics in Medicine

Volume: 23, P: 123-130
Muc16 depletion diminishes KRAS-induced tumorigenesis and metastasis by altering tumor microenvironment factors in pancreatic ductal adenocarcinoma

Imayavaramban Lakshmanan
Saravanakumar Marimuthu
Surinder K. Batra
Research21 Oct 2022
Oncogene

Volume: 41, P: 5147-5159
Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines

Troy C. Sutton
Saborni Chakraborty
Kanta Subbarao
ResearchOpen Access15 Dec 2017
npj Vaccines

Volume: 2, P: 1-11
Factors affecting the development of atrial fibrillation and atrial flutter (AF/AFL) following autologous hematopoietic SCT (auto-HSCT)

J A Steuter
M L H Villanueva
P J Bierman
Research10 Dec 2012
Bone Marrow Transplantation

Volume: 48, P: 963-965
MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling

I Lakshmanan
S Rachagani
A K Ganti
Research11 Jan 2016
Oncogene

Volume: 35, P: 4112-4121
MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway

M A Macha
S Rachagani
S K Batra
Research21 Apr 2014
Oncogene

Volume: 34, P: 1698-1708

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