Primary CNS lymphoma (PCNSL) is a rare malignancy with an aggressive course, for which treatment has yet to be optimized. Here, Korfel and Schlegel discuss diagnostic approaches in patients with suspected PCNSL, and review the latest studies on new and more established therapeutic interventions. Ongoing issues—including the utility of whole-brain radiotherapy, and treatment of young, elderly and immunocompromised patients—are also considered.
- Agnieszka Korfel
- Uwe Schlegel