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Showing 101–150 of 166 results

Advanced filters: Author: A. FARRINGTON Clear advanced filters

Mechanisms of Disease: the hypoxic tubular hypothesis of diabetic nephropathy

Traditionally thought of as a primarily glomerular disease, evidence is accumulating to support early involvement of tubular and interstitial dysfunction in the development of diabetic nephropathy. This Review focuses on the role of chronic hypoxia in the tubulointerstitium as a major factor in the pathogenesis of diabetic nephropathy, and touches on the status of potentially beneficial clinical interventions.

Dhruv K Singh
Peter Winocour
Ken Farrington
Reviews12 Feb 2008
Nature Clinical Practice Nephrology

Volume: 4, P: 216-226
Science Teachers in Conference

A. T. SIMMONS
News17 Jan 1901
Nature

Volume: 63, P: 289-290
Detergents, Textiles and Dyes

A. S. C. LAWRENCE
News02 May 1959
Nature

Volume: 183, P: 1236-1238
The relationship between criminology and criminal law: implications for developing Chinese criminology

Honglan Shuai
Jianhong Liu
ResearchOpen Access23 Jun 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-11
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

Richard Houlston and colleagues identify four new susceptibility loci for colorectal cancer through a meta-analysis of genome-wide association data, followed by replication testing in a large collection of independent samples. The study brings to ten the number of confirmed loci harboring low-penetrance risk alleles for this common malignancy.

Richard S Houlston
Emily Webb
Malcolm G Dunlop
Research16 Nov 2008
Nature Genetics

Volume: 40, P: 1426-1435
Germany’s fourth COVID-19 wave was mainly driven by the unvaccinated

Maier et al. develop a mathematical model to examine the contributions of vaccinated vs. unvaccinated populations to the wave of SARS-CoV-2 infections in Germany in autumn 2021. They report that the unvaccinated population were the main drivers of transmission and that targeted non-pharmaceutical interventions would likely have mitigated this.

Benjamin F. Maier
Marc Wiedermann
Dirk Brockmann
ResearchOpen Access16 Sept 2022
Communications Medicine

Volume: 2, P: 1-9
Heavy metals bioconcentration in Crassostrea rhizophorae: A site-to-site transplant experiment at the Potengi estuary, Rio Grande do Norte, Brazil

T. M. Senez-Mello
M. A. C. Crapez
E. M. Fonseca
ResearchOpen Access14 Jan 2020
Scientific Reports

Volume: 10, P: 1-13
Measurement of Li⁺ Ion Transport Numbers in Poly(ethylene oxide)–LiX Complexes

M Z A Munshi
B B Owens
S Nguyen
Research01 Jul 1988
Polymer Journal

Volume: 20, P: 597-602
Joining the Islamic State from France between 2014 and 2016: an observational follow-up study

Nicolas Campelo
Laura Bouzar
Dounia Bouzar
ResearchOpen Access14 Nov 2018
Palgrave Communications

Volume: 4, P: 1-10
Met 235 the polymorphism of angiotensinogen in indonesians

M. Mansyur Romi
Suryono Yudha Patria
Masafumi Matsuo
Research01 Dec 1997
Japanese Journal of Human Genetics

Volume: 42, P: 557-559
Exploration of different classes of metrics to characterize motor variability during repetitive symmetric and asymmetric lifting tasks

Alireza Sedighi
Maury A. Nussbaum
ResearchOpen Access08 Jul 2019
Scientific Reports

Volume: 9, P: 1-9
Syndromic surveillance of abortions in beef cattle based on the prospective analysis of spatio-temporal variations of calvings

A. Bronner
E. Morignat
D. Calavas
ResearchOpen Access21 Dec 2015
Scientific Reports

Volume: 5, P: 1-10
The expanding fireball of Nova Delphini 2013

High spatial resolution is needed to study the early development of a nova; here measurements of the angular size and radial velocity of Nova Delphini 2013 reveal early structures in the ejected material and a geometric distance to the nova of about 4.5 kiloparsecs from the Sun.

G. H. Schaefer
T. ten Brummelaar
P. S. Muirhead
Research26 Oct 2014
Nature

Volume: 515, P: 234-236
Trans-ancestry transcriptome-wide association and functional studies to uncover novel susceptibility genes and therapeutic targets for colorectal cancer

Lijuan Wang
Lidan Hu
Xue Li
ResearchOpen Access29 Apr 2025
npj Precision Oncology

Volume: 9, P: 1-10
Erythropoietic stress and anemia in diabetes mellitus

Chronic hyperglycemia in diabetes mellitus can lead to erythropoietic stress and subsequent anemia, which might contribute to diabetes-related complications. The authors of this Review discuss the various causes of diabetes-related anemia and current guidelines on its correction, and emphasize the role of screening and monitoring for this preventable condition in patients with diabetes mellitus.

Dhruv K. Singh
Peter Winocour
Ken Farrington
Reviews01 Apr 2009
Nature Reviews Endocrinology

Volume: 5, P: 204-210
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

Ian Tomlinson, Richard Houlston, Malcolm Dunlop and colleagues report results of a large genome-wide association study of colorectal cancer. They identify four new risk loci and suggest that many more loci of similar effect size are likely to exist.

Richard S Houlston
Jeremy Cheadle
Ian P M Tomlinson
Research24 Oct 2010
Nature Genetics

Volume: 42, P: 973-977
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

Ian PM Tomlinson
Emily Webb
Richard S Houlston
Research30 Mar 2008
Nature Genetics

Volume: 40, P: 623-630
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

Community microattribution review of the evidence for colon cancer risk conferred by constitutional variants in MLH1, MSH2, MSH6 and PMS2 has resulted in the reclassification of two-thirds of the variants reported in existing databases and led to clinical recommendations for the interpretation of 1,370 variants that do not result in obvious protein truncation.

Bryony A Thompson
Amanda B Spurdle
Victor-Manuel Barbera
Research22 Dec 2013
Nature Genetics

Volume: 46, P: 107-115
Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach

J J P Gille
F B L Hogervorst
F H Menko
ResearchOpen Access07 Oct 2002
British Journal of Cancer

Volume: 87, P: 892-897
Relationships of PGRN with sTREM2 in AD continuum and non-AD pathophysiology and their reciprocal roles in modulating amyloid pathology: two population-based study

Liang-Yu Huang
Chen-Chen Tan
Dariella Fernandez
ResearchOpen Access08 Jul 2025
Translational Psychiatry

Volume: 15, P: 1-11
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

Richard Houlston and colleagues report a genome-wide association study for colorectal cancer. They report three loci newly associated with colorectal cancer, bringing the total number of common susceptibility loci to 20.

Malcolm G Dunlop
Sara E Dobbins
Richard S Houlston
Research27 May 2012
Nature Genetics

Volume: 44, P: 770-776
Contribution of Sp1 to initiation of transcription of angiotensinogen

A. Rohrwasser
S. Zhang
J.-M. Lalouel
Research01 May 2002
Journal of Human Genetics

Volume: 47, P: 249-256
Ionic Transport in Poly(ethylene oxide) (PEO)-LiX Polymeric Solid Electrolyte

M Z A Munshi
B B Owens
Research01 Jul 1988
Polymer Journal

Volume: 20, P: 577-586
Idoxifene is equipotent to tamoxifen in inhibiting mammary carcinogenesis but forms lower levels of hepatic DNA adducts

P Pace
M Jarman
RC Coombes
Research01 Sept 1997
British Journal of Cancer

Volume: 76, P: 700-704
Mismatch repair genes and mononucleotide tracts as mutation targets in colorectal tumors with different degrees of microsatellite instability

Antonio Percesepe
Paula Kristo
Päivi Peltomäki
Research17 Jul 1998
Oncogene

Volume: 17, P: 157-163
Molecular pathogenesis of sporadic duodenal cancer

A Achille
A Baron
A Scarpa
Research01 Mar 1998
British Journal of Cancer

Volume: 77, P: 760-765
Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers

Lisa A Simms
Graham Radford-Smith
Barbara A Leggett
Research14 Oct 1998
Oncogene

Volume: 17, P: 2003-2008
Genetic analysis of the APC gene regions involved in attenuated APC phenotype in Israeli patients with early onset and familial colorectal cancer

A Figer
L Irmin
E Friedman
ResearchOpen Access14 Aug 2001
British Journal of Cancer

Volume: 85, P: 523-526
Effects of surgically induced weight loss on urinary bladder pressure, sagittal abdominal diameter and obesity co-morbidity

H Sugerman
A Windsor
E DeMaria
Research20 Apr 1998
International Journal of Obesity

Volume: 22, P: 230-235
Bullying in schoolchildren – its relationship to dental appearance and psychosocial implications: an update for GDPs

J. Seehra
J. T. Newton
A. T. DiBiase
Research13 May 2011
British Dental Journal

Volume: 210, P: 411-415
The effects of norethisterone on endometrial abnormalities identified by transvaginal ultrasound screening of healthy post-menopausal women on tamoxifen or placebo

TJ Powles
T Bourne
W Collins
Research01 Jul 1998
British Journal of Cancer

Volume: 78, P: 272-275
Prognostic significance of folate metabolism polymorphisms for lung cancer

A Matakidou
R el Galta
R S Houlston
ResearchOpen Access29 May 2007
British Journal of Cancer

Volume: 97, P: 247-252
In silico drug discovery: Tools for bridging the NCE gap

Bruno L. Larvol
L. John Wilkerson
Comments & Opinion01 May 1998
Nature Biotechnology

Volume: 16, P: 33-34
Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Ceres Fernandez-Rozadilla
Maria Timofeeva
Ulrike Peters
Amendments and Corrections13 Feb 2023
Nature Genetics

Volume: 55, P: 519-520
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

G. Aad
B. Abbott
L. Zwalinski
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E5
Common genetic variants at the MC4R locus are associated with obesity, but not with dietary energy intake or colorectal cancer in the Scottish population

A Tenesa
H Campbell
M G Dunlop
Research09 Dec 2008
International Journal of Obesity

Volume: 33, P: 284-288
A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

Nada A. Al-Tassan
Nicola Whiffin
Richard S. Houlston
ResearchOpen Access20 May 2015
Scientific Reports

Volume: 5, P: 1-11
Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer

Maria N. Timofeeva
Ben Kinnersley
Richard S. Houlston
ResearchOpen Access10 Nov 2015
Scientific Reports

Volume: 5, P: 1-10
Plasma N-glycans in colorectal cancer risk

Margaret Doherty
Evropi Theodoratou
Pauline M. Rudd
ResearchOpen Access05 Jun 2018
Scientific Reports

Volume: 8, P: 1-12
Comparison of resting and total energy expenditure in peritoneal dialysis patients and body composition measured by dual-energy X-ray absorptiometry

S El-Kateb
S Sridharan
A Davenport
Research06 Jul 2016
European Journal of Clinical Nutrition

Volume: 70, P: 1337-1339
Association studies on 11 published colorectal cancer risk loci

S von Holst
S Picelli
A Lindblom
ResearchOpen Access20 Jul 2010
British Journal of Cancer

Volume: 103, P: 575-580
Functional identification of LZTS1 as a candidate prostate tumor suppressor gene on human chromosome 8p22

Yofre Cabeza-Arvelaiz
Jorge L Sepulveda
A Craig Chinault
Research17 Jul 2001
Oncogene

Volume: 20, P: 4169-4179
Prophylaxis and treatment of chemo- and radiotherapy-induced oral mucositis – are there new strategies?

M Karthaus
C Rosenthal
A Ganser
Research10 Nov 1999
Bone Marrow Transplantation

Volume: 24, P: 1095-1108
Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure

Prasanna Jagannathan
Fredrick Lutwama
Margaret E. Feeney
ResearchOpen Access13 Sept 2017
Scientific Reports

Volume: 7, P: 1-12
Rhinoceros horn mineral and metal concentrations vary by sample location, depth, and color

Terri L. Roth
Sarah L. Rebolloso
John P. Buchweitz
ResearchOpen Access14 Jun 2024
Scientific Reports

Volume: 14, P: 1-13
Lymphoid abnormalities in CD40 ligand transgenic mice suggest the need for tight regulation in gene therapy approaches to hyper immunoglobulin M (IgM) syndrome

Maria Grazia Sacco
Marco Ungari
Paolo Vezzoni
Research01 Oct 2000
Cancer Gene Therapy

Volume: 7, P: 1299-1306
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1

Timothy HT Cheng
Deborah Thompson
Ian Tomlinson
ResearchOpen Access01 Dec 2015
Scientific Reports

Volume: 5, P: 1-12
New insights into the aetiology of colorectal cancer from genome-wide association studies

Recent studies have identified common genetic variants that contribute to colorectal cancer aetiology, providing new insight into the genetic architecture of the disease. Associations identified so far suggest an overlap with familial cases in terms of biological mechanisms, and also provide new avenues for exploration.

Albert Tenesa
Malcolm G. Dunlop
Reviews01 Jun 2009
Nature Reviews Genetics

Volume: 10, P: 353-358
Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patients

A S Soliman
M L Bondy
S R Hamilton
ResearchOpen Access02 Oct 2001
British Journal of Cancer

Volume: 85, P: 1037-1046
High resolution chromosome 3p, 8p, 9q and 22q allelotyping analysis in the pathogenesis of gallbladder carcinoma

I I Wistuba
A Maitra
A F Gazdar
ResearchOpen Access06 Aug 2002
British Journal of Cancer

Volume: 87, P: 432-440

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