Recent studies have indicated that the recognition of microorganism-associated molecular patterns (MAMPs) by G protein-coupled receptors (GPCRs) involves a larger set of chemotactic MAMPs and corresponding GPCRs than was previously thought. Peschel and colleagues review bacterial leukocyte-attracting molecules, the corresponding human receptors, and their roles in antibacterial host defence.
- Dominik Alexander Bloes
- Dorothee Kretschmer
- Andreas Peschel