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Zebrafish model of palmitic acid induced MAFLD recapitulates pathways conserved in mice and humans

Debashruti Bhattacharya
Shruti Kaushal
Shilpi Minocha
ResearchOpen Access29 Sept 2025
Scientific Reports

Volume: 15, P: 1-21
Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein

Lanthipeptides are a class of cyclic post-translationally modified peptides with potential drug-like properties. Here the authors develop a phage display system by expressing lanthipeptide precursors as C-terminal fusions to the phage M13 coat protein pIII in E. coli along with the heterologous modifying enzymes.

Johannes H. Urban
Markus A. Moosmeier
Josef Prassler
ResearchOpen Access15 Nov 2017
Nature Communications

Volume: 8, P: 1-10
Interaction-driven localization in holography

Strongly interacting condensed-matter systems are often computationally intractable. By introducing a periodic lattice to a holographic model developed by string theorists, it becomes possible to study anisotropic materials that are insulating in certain directions but conducting in others.

Aristomenis Donos
Sean A. Hartnoll
Research11 Aug 2013
Nature Physics

Volume: 9, P: 649-655
Piezo1 regulates the mechanotransduction of soft matrix viscoelasticity

Matrix viscoelasticity regulates cell behavior in a stiffness-dependent manner. Here, the authors reveal that the mechanosensitive channel Piezo1 transduces soft matrix viscoelastic cues, through a coordinated interaction with molecular clutch mechanisms.

Mariana A. G. Oliva
Giuseppe Ciccone
Manuel Salmeron-Sanchez
ResearchOpen Access15 Oct 2025
Nature Communications

Volume: 16, P: 1-18
Bile salt hydrolase acyltransferase activity expands bile acid diversity

Acyltransferase activity of the enzyme bile salt hydrolase is identified and shown to mediate microbial bile acid conjugation, diversifying the bile acid pool and expanding their role in gut physiology.

Douglas V. Guzior
Maxwell Okros
Robert A. Quinn
Research07 Feb 2024
Nature

Volume: 626, P: 852-858
Spectrum of Rubidium Hydride, RbH

A. G. GAYDON
R. W. B. PEARSE
Research13 Aug 1938
Nature

Volume: 142, P: 291
An Automatic Recording Infra-Red Spectrometer

I. A. BROWNLIE
W. M. CUMMING
Research16 Jul 1949
Nature

Volume: 164, P: 105-106
Substrate control in stereoselective lanthionine biosynthesis

The stereochemical outcome of enzyme-catalysed reactions with physiological substrates is typically governed by the well-defined geometry of the enzyme active site. Now, a rare example is reported where the substrate controls the stereoselectivity of a Michael-type addition during lanthipeptide biosynthesis.

Weixin Tang
Gonzalo Jiménez-Osés
Wilfred A. van der Donk
Research24 Nov 2014
Nature Chemistry

Volume: 7, P: 57-64
A lanthipeptide library used to identify a protein–protein interaction inhibitor

The substrate-tolerant lanthipeptide synthetase ProcM enables the construction of a plasmid-encoded library of bicyclic lanthipeptides, from which an inhibitor of the p6–UEV protein–protein interaction is identified by a reverse two-hybrid screen.

Xiao Yang
Katherine R. Lennard
Wilfred A. van der Donk
Research05 Mar 2018
Nature Chemical Biology

Volume: 14, P: 375-380
Further Experiments on Liquid Helium II

A. K. KIKOIN
B. G. LASAREW
Research13 Aug 1938
Nature

Volume: 142, P: 289-290
Action of Procaine on Calcium Efflux from Frog Nerve and Muscle

ALBERT S. KUPERMAN
BELLA T. ALTURA
JUDITH A. CHEZAR
Research17 Feb 1968
Nature

Volume: 217, P: 673-675
Non-conservative Fundamental Particles

A. PROCA
Research25 Nov 1944
Nature

Volume: 154, P: 674
N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity

The crosstalk between cell-cell and cell-matrix adhesions regulates stem cell fate. Here, the authors reveal a critical role for matrix viscosity in controlling this crosstalk, which they explain via a modified molecular clutch model.

Eva Barcelona-Estaje
Mariana A. G. Oliva
Manuel Salmeron-Sanchez
ResearchOpen Access12 Oct 2024
Nature Communications

Volume: 15, P: 1-12
The laminin–keratin link shields the nucleus from mechanical deformation and signalling

Laminin, an important component of the extracellular matrix supporting the epithelium, hinders the typical mechanoresponse of epithelial cells to an increase in substrate stiffness, by protecting the cell nucleus from mechanical deformation.

Zanetta Kechagia
Pablo Sáez
Pere Roca-Cusachs
ResearchOpen Access14 Sept 2023
Nature Materials

Volume: 22, P: 1409-1420
Mechanical force application to the nucleus regulates nucleocytoplasmic transport

Andreu et al. show that force regulates nucleocytoplasmic transport by weakening the permeability barrier of nuclear pore complexes, affecting passive and facilitated diffusion in different ways.

Ion Andreu
Ignasi Granero-Moya
Pere Roca-Cusachs
Research09 Jun 2022
Nature Cell Biology

Volume: 24, P: 896-905

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