Nature Search

Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia

Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with dementia.

Carmen Gasca-Salas
Beatriz Fernández-Rodríguez
José A. Obeso
ResearchOpen Access03 Feb 2021
Nature Communications

Volume: 12, P: 1-7
Ecological effects of stress drive bacterial evolvability under sub-inhibitory antibiotic treatments

Marie Vasse
Sebastian Bonhoeffer
Antoine Frenoy
ResearchOpen Access02 Sept 2022
ISME Communications

Volume: 2, P: 1-7
β-lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity

Sub-lethal concentrations of antibiotics are known to promote mutagenesis of bacterial DNA. Here the authors show that β-lactam antibiotics trigger mutagenesis by upregulating the stress-response protein RpoS, which downregulates mismatch-repair activity.

A. Gutierrez
L. Laureti
I. Matic
ResearchOpen Access19 Mar 2013
Nature Communications

Volume: 4, P: 1-9
Decomposing virulence to understand bacterial clearance in persistent infections

The relationship between virulence and pathogen clearance is not well understood. Here, using bacterial infections in Drosophila melanogaster as a model system, the authors demonstrate an approach to disentangle the drivers of virulence and assess their relation to pathogen clearance rate.

Beatriz Acuña Hidalgo
Luís M. Silva
Sophie A. O. Armitage
ResearchOpen Access26 Aug 2022
Nature Communications

Volume: 13, P: 1-14
Quantitative and qualitative impact of hospital effluent on dissemination of the integron pool

Thibault Stalder
Olivier Barraud
Marie- Cécile Ploy
Research24 Oct 2013
The ISME Journal

Volume: 8, P: 768-777
Dopaminergic denervation and associated MRI microstructural changes in the nigrostriatal projection in early Parkinson’s disease patients

M. López-Aguirre
M. Matarazzo
J. A. Pineda-Pardo
ResearchOpen Access19 Oct 2023
npj Parkinson's Disease

Volume: 9, P: 1-8
Gut microbiome signatures of Yorkshire Terrier enteropathy during disease and remission

Pavlos G. Doulidis
Alexandra I. Galler
Iwan A. Burgener
ResearchOpen Access16 Mar 2023
Scientific Reports

Volume: 13, P: 1-11
Clay-induced DNA breaks as a path for genetic diversity, antibiotic resistance, and asbestos carcinogenesis

Enrique González-Tortuero
Jerónimo Rodríguez-Beltrán
Alexandro Rodríguez-Rojas
ResearchOpen Access31 May 2018
Scientific Reports

Volume: 8, P: 1-10

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