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Showing 1–2 of 2 results
Advanced filters: Author: Aarti Jajoo Clear advanced filters

  • Genetic models for psychiatric disorders often overlook ancestry diversity. Here, the authors use PsychENCODE and GWAS data to build ancestry-specific GReX models, improving TWAS and revealing novel genes and pathways linked to brain development and psychiatric risk.

    • Aarti Jajoo
    • Vijetha Balakundi
    • Nikolaos P. Daskalakis
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-21

  • The edematous form of severe acute childhood malnutrition (ESAM) presents with more severe multi-organ dysfunction than non-edematous SAM (NESAM). Here the authors assess genome-wide DNA methylation in buccal cells of SAM children and find that ESAM is characterized by hypomethylation at genes associated with disorders of nutrition and metabolism, including fatty liver and diabetes.

    • Katharina V. Schulze
    • Shanker Swaminathan
    • Neil A. Hanchard
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13