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Advanced filters: Author: Abir Bhattacharjee Clear advanced filters

Bioactive molecules unearthed by terabase-scale long-read sequencing of a soil metagenome

Optimized long-read sequencing constructs megabase-scale genome assemblies from complex soil samples.

Ján Burian
Robert E. Boer
Sean F. Brady
ResearchOpen Access12 Sept 2025
Nature Biotechnology

P: 1-8
M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome

CQ31 inhibits the M24B aminopeptidases prolidase and Xaa-Pro aminopeptidase 1 leading to increased proline-containing peptides that block dipeptidyl peptidases 8 and 9 activity resulting in the activation of the CARD8 inflammasome.

Sahana D. Rao
Qifeng Chen
Daniel A. Bachovchin
Research14 Feb 2022
Nature Chemical Biology

Volume: 18, P: 565-574
Andrographolide binds to ATP-binding pocket of VEGFR2 to impede VEGFA-mediated tumor-angiogenesis

Kirti Kajal
Abir K. Panda
Gaurisankar Sa
ResearchOpen Access11 Mar 2019
Scientific Reports

Volume: 9, P: 1-10