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Advanced filters: Author: Adéla Tiffner Clear advanced filters

  • The Ca2+ ion channel Orai1 plays an important role in T-cell activation. A charged amino acid side chain close to the center of Orai1-transmembrane domain (TM)3 or -TM4 triggers robust constitutive activity due to enhanced hydration and widening of peripheral TM-interfaces.

    • Valentina Hopl
    • Adéla Tiffner
    • Isabella Derler
    ResearchOpen Access
    Communications Biology
    Volume: 7, P: 1-16