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Showing 1–3 of 3 results
Advanced filters: Author: Aditi Trehan Clear advanced filters

  • Combining genome-wide CRISPR screens with massively parallel analyses of human and random DNA sequences reveal a unified mechanism for the surveillance and evolution of translation products from annotated noncoding DNA.

    • Jordan S. Kesner
    • Ziheng Chen
    • Xuebing Wu
    Research
    Nature
    Volume: 617, P: 395-402

  • How the 22q11.2 deletion predisposes to psychiatric disease is unclear. Here, the authors examine living human neuronal cells and show that 22q11.2 regulates the expression of genes linked to autism during early development, and genes linked to schizophrenia and synaptic biology in neurons.

    • Ralda Nehme
    • Olli Pietiläinen
    • Kevin Eggan
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-21