Congenital anomalies of the kidneys and/or lower urinary tract are the major cause of childhood end-stage renal disease, and they can also present in adulthood. Kerecuk et al. summarize the anatomical and histological features of renal tract malformations, the best approaches to prenatal and postnatal diagnosis of these conditions, and the influence of genetic and environmental factors in their etiology. The utility of therapeutic intervention is also considered.
- Larissa Kerecuk
- Michiel F Schreuder
- Adrian S Woolf
