Multispecific antibody constructs that bind several distinct targets can connect cells and/or simultaneously target multiple molecules. Here, Lub-de Hooge et al. discuss the varied contributions of molecular imaging to multispecific antibody design, drug development and optimization, including evaluations of antibody biodistribution and pharmacological complexity.
- Claudia A. J. van Winkel
- Frank R. Pierik
- Marjolijn N. Lub-de Hooge
