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  • It is currently unknown how environmental cues regulate ciliary Polycystin ion channels on renal epithelial cells. Here authors identify a cilia-enriched oxysterol, 7β,27- dihydroxycholesterol (DHC), as a necessary activator of the polycystin complex

    • Kodaji Ha
    • Nadine Mundt-Machado
    • Markus Delling
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13