Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Nature Communications (3)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (3)

Subject Check one or more subjects to show results from those subjects only.

Biological techniques
Evolution
Microbiology
Molecular biology
Systems biology

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–3 of 3 results

Advanced filters: Author: Alaksh Choudhury Clear advanced filters

Deep mutational scanning reveals the molecular determinants of RNA polymerase-mediated adaptation and tradeoffs

Mutations in an RNA polymerase fragment, frequently found in lab adaptation, cluster in two modules favoring growth or maintenance via loss of interactions. Combining mutations in both modules enhances both traits, promoting compensatory evolution.

Alaksh Choudhury
Benoit Gachet
Olivier Tenaillon
ResearchOpen Access09 Oct 2023
Nature Communications

Volume: 14, P: 1-16
Small molecule regulated sgRNAs enable control of genome editing in E. coli by Cas9

Bacteria lack the same suite of CRISPR tools that have been developed for mammalian cells. Here, the authors link aptamers to sgRNAs to allow small molecule control of gene editing in E. coli.

Roman S. Iwasaki
Bagdeser A. Ozdilek
Robert T. Batey
ResearchOpen Access13 Mar 2020
Nature Communications

Volume: 11, P: 1-9
Engineering regulatory networks for complex phenotypes in E. coli

Regulatory networks respond to environmental and genetic perturbations by reprogramming metabolism. Here the authors screen a library of 82 regulators with 110,120 mutations to map the regulatory network of 4000 genes.

Rongming Liu
Liya Liang
Ryan T. Gill
ResearchOpen Access13 Aug 2020
Nature Communications

Volume: 11, P: 1-13