The striatum contains two distinct types of GABAergic neurons, striatonigral and striatopallidal cells. Durieux and colleagues genetically ablated the striatopallidal population in mice, uncovering specific roles for these neurons in the control of locomotion and the response to the addictive drug amphetamine.
- Pierre F Durieux
- Bertrand Bearzatto
- Alban de Kerchove d'Exaerde