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Showing 1–6 of 6 results
Advanced filters: Author: Aldo J. Montano-Loza Clear advanced filters

  • The authors of this Review discuss current indications for treatment in patients with autoimmune hepatitis, conventional management regimens, therapeutic end points and treatment outcomes. Factors that influence the treatment response, empiric salvage therapies, and promising pharmacological and molecular interventions are also considered.

    • Aldo J Montano Loza
    • Albert J Czaja
    Reviews
    Nature Clinical Practice Gastroenterology & Hepatology
    Volume: 4, P: 202-214

  • Autoimmune hepatitis (AIH) is a severe liver disease in which loss of tolerance against the patient's own liver antigens, probably triggered by environmental agents, occurs in genetically susceptible individuals. This Primer explores the current understanding of AIH and outlines future research priorities.

    • Giorgina Mieli-Vergani
    • Diego Vergani
    • Aldo J. Montano-Loza
    Reviews
    Nature Reviews Disease Primers
    Volume: 4, P: 1-21

  • Immune dysregulation is a main feature of chronic liver disease, whose burden increases worldwide. This Review discusses the influence of biological sex in hepatic immune mechanisms in the context of liver disease and identifies sex disparities in research and therapeutics.

    • Patrizia Burra
    • Alberto Zanetto
    • Frank Tacke
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 21, P: 869-884