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Showing 1–8 of 8 results
Advanced filters: Author: Alejandro Forner Clear advanced filters

  • The treatment options available for hepatocellular carcinoma (HCC) vary depending on prognostic factors that include tumour characteristics and clinical status, particularly with regard to liver function. This Review discusses the links between disease phenotype, prognosis and therapy, focusing on the subclassification of patients with intermediate-stage HCC following the BCLC staging system, who are usually ineligible for curative resection and ablation treatments or liver transplantation; the therapies that are available for this patient subgroup are described.

    • Alejandro Forner
    • Marine Gilabert
    • Jean-Luc Raoul
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 11, P: 525-535

  • Combined hepatocellular-cholangiocarcinomas (cHCC-CCA) are challenging to diagnose, as they exhibit features of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICCA). Here, the authors use deep learning to re-classify cHCC-CCA tumours into HCC or ICCA based on histopathology images.

    • Julien Calderaro
    • Narmin Ghaffari Laleh
    • Jakob Nikolas Kather
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-10

  • Preclinical research is required to improve our understanding of cholangiocarcinoma (CCA). In this Consensus Statement, a task force of experts provides recommendations on the criteria for preclinical models of CCA to increase disease understanding and help to develop novel therapeutic approaches.

    • Diego F. Calvisi
    • Luke Boulter
    • Yoshimasa Saito
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 20, P: 462-480

  • Cholangiocarcinoma (CCA) comprises heterogeneous biliary malignant tumours, and their incidence is increasing worldwide. This expert Consensus Statement, endorsed by the ENS-CCA, summarizes the latest advances in CCA, including classification, genetics and treatment, and provides recommendations for CCA management and priorities across basic, translational and clinical research.

    • Jesus M. Banales
    • Jose J. G. Marin
    • Gregory J. Gores
    ReviewsOpen Access
    Nature Reviews Gastroenterology & Hepatology
    Volume: 17, P: 557-588