A combination of growth factors and the transcription factor Neurogenin2 has been shown to enhance the production of new neurons from endogenous cells. Here Grandeet al.demonstrate in a rat brain injury model that these factors reprogramme non-neuronal cells into different neuronal phenotypes at distinct efficiencies depending on the environment the cells reside in.
- Andrew Grande
- Kyoko Sumiyoshi
- Masato Nakafuku
