Circadian clocks enable organisms to anticipate daily cycles, while being robust to molecular and environmental noise. Here, Eremina et al. show how the cyanobacterial clock buffers genetic and environmental perturbations through its core phosphorylation loop, and demonstrate that known clock regulators are dispensable for clock robustness.
- Aleksandra Eremina
- Christian Schwall
- James C. W. Locke
