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Showing 1–3 of 3 results
Advanced filters: Author: Alex Rivera-Millot Clear advanced filters

  • Site-specific endonucleases that exclusively cut single-stranded DNA have hitherto never been described and constitute a barrier to the development of ssDNA-based technologies. Here the authors identify and characterize a family of such enzymes that could be the basis of innovative molecular tools.

    • Martin Chenal
    • Alex Rivera-Millot
    • Frédéric J. Veyrier
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15

  • Alex Rivera-Millot et al. investigate copper homeostasis in the whooping cough agent Bordetella pertussis, which has a single copper defense mechanism via a metallochaperone diverted for copper passivation and two peroxide detoxification enzymes. This study demonstrates that copper up-regulates the copZ-prxgrx-gorB operon in macrophages, and this system appears to contribute to persistent infection in the nasal cavity of B. pertussis-infected mice. This study brings insight into strategies aimed to optimize survival of a host-restricted pathogen.

    • Alex Rivera-Millot
    • Stéphanie Slupek
    • Françoise Jacob-Dubuisson
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-12

  • Rod-shaped bacteria typically elongate and divide by transverse fission, but a few species are known to divide longitudinally. Here, the authors use genomic, phylogenetic and microscopy techniques to shed light on the evolution of cell shape, multicellularity and division mode within the family Neisseriaceae.

    • Sammy Nyongesa
    • Philipp M. Weber
    • Frédéric J. Veyrier
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18