Because clathrin-mediated endocytosis (CME) is relatively slow, it's been suggested that a readily retrievable pool of synaptic vesicle proteins might support fast CME. The authors use a recently developed probe to monitor synaptic vesicle recycling and demonstrate the preferential recruitment of a surface pool of synaptic vesicle proteins upon stimulated endocytosis.
- Yunfeng Hua
- Raunak Sinha
- Jurgen Klingauf