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Showing 1–12 of 12 results

Advanced filters: Author: Alexander Predeus Clear advanced filters

A single-cell and spatial genomics atlas of human skin fibroblasts reveals shared disease-related fibroblast subtypes across tissues

Steele et al. use single-cell RNA sequencing and spatial transcriptomics to provide an atlas of adult human skin fibroblasts in healthy and diseased human skin.

Lloyd Steele
Bayanne Olabi
Muzlifah Haniffa
ResearchOpen Access24 Sept 2025
Nature Immunology

Volume: 26, P: 1807-1820
A spatial human thymus cell atlas mapped to a continuous tissue axis

A quantitative morphological framework for the human thymus reveals the establishment of the lobular cytokine network, canonical thymocyte trajectories and thymic epithelial cell distributions in fetal and paediatric thymic development.

Nadav Yayon
Veronika R. Kedlian
Sarah A. Teichmann
ResearchOpen Access20 Nov 2024
Nature

Volume: 635, P: 708-718
A multi-omic atlas of human embryonic skeletal development

A multiomic atlas of human embryonic joint and cranium development enables detailed analysis of bone and cartilage maturation.

Ken To
Lijiang Fei
Sarah A. Teichmann
ResearchOpen Access20 Nov 2024
Nature

Volume: 635, P: 657-667
Single-cell integration reveals metaplasia in inflammatory gut diseases

The study provides a comprehensive transcriptomic atlas of the human gastrointestinal tract across the lifespan, highlighting inflammation-induced changes in epithelial stem cells that alter mucosal architecture and promote further inflammation.

Amanda J. Oliver
Ni Huang
Sarah A. Teichmann
ResearchOpen Access20 Nov 2024
Nature

Volume: 635, P: 699-707
Single-cell and spatially resolved interactomics of tooth-associated keratinocytes in periodontitis

Here, Easter et al. generate a single-cell atlas of human periodontium including sulcular and junctional keratinocytes. Cell-cell communication analysis is used to predict keratinocyte-specific immune cell interactions.

Quinn T. Easter
Bruno Fernandes Matuck
Kevin M. Byrd
ResearchOpen Access14 Jun 2024
Nature Communications

Volume: 15, P: 1-23
Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa

Stepwise evolution of invasive Salmonella Typhimurium in Africa is defined using genotypic and phenotypic analyses of isolates collected over a 50-yr period.

Caisey V. Pulford
Blanca M. Perez-Sepulveda
Jay C. D. Hinton
ResearchOpen Access21 Dec 2020
Nature Microbiology

Volume: 6, P: 327-338
Phenome-wide functional dissection of pleiotropic effects highlights key molecular pathways for human complex traits

Anton E. Shikov
Rostislav K. Skitchenko
Yury A. Barbitoff
ResearchOpen Access23 Jan 2020
Scientific Reports

Volume: 10, P: 1-10
Catching hidden variation: systematic correction of reference minor allele annotation in clinical variant calling

Yury A Barbitoff
Igor V Bezdvornykh
Alexander V Predeus
Research26 Oct 2017
Genetics in Medicine

Volume: 20, P: 360-364
LMNA R482L mutation causes impairments in C2C12 myoblasts subpopulations, alterations in metabolic reprogramming during differentiation, and oxidative stress

Oksana A. Ivanova
Alexander V. Predeus
Renata I. Dmitrieva
ResearchOpen Access13 Feb 2025
Scientific Reports

Volume: 15, P: 1-22
Author Correction: Transcriptomic profiling of Escherichia coli K-12 in response to a compendium of stressors

Rama P. Bhatia
Hande A. Kirit
Jonathan P. Bollback
Amendments and CorrectionsOpen Access07 Oct 2022
Scientific Reports

Volume: 12, P: 1
Systematic dissection of biases in whole-exome and whole-genome sequencing reveals major determinants of coding sequence coverage

Yury A. Barbitoff
Dmitrii E. Polev
Alexander V. Predeus
ResearchOpen Access06 Feb 2020
Scientific Reports

Volume: 10, P: 1-13
Transcriptomic profiling of Escherichia coli K-12 in response to a compendium of stressors

Rama P. Bhatia
Hande A. Kirit
Jonathan P. Bollback
ResearchOpen Access24 May 2022
Scientific Reports

Volume: 12, P: 1-14