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Showing 1–6 of 6 results

Advanced filters: Author: Alexander Ulges Clear advanced filters

It takes CK2 to suppress T_H2

Optimal immunosuppression by regulatory T cells (T_reg cells) relies on gene-expression and signaling modules that are customized to the target cell. The kinase CK2 is upregulated in T_reg cells and controls a newly identified T_reg cell subset that acts on dendritic cells to suppress T helper type 2 inflammatory responses in the lungs.

Deepali V Sawant
Alexander L Dent
News & Views17 Feb 2015
Nature Immunology

Volume: 16, P: 224-225
Author Correction: BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

Uğur Şahin
Alexander Muik
Özlem Türeci
Amendments and Corrections16 Jul 2025
Nature

Volume: 643, P: E27
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

In a phase-I/II trial in healthy adults, the BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells against SARS-CoV-2 epitopes that are conserved in a wide range of currently circulating variants.

Ugur Sahin
Alexander Muik
Özlem Türeci
Research27 May 2021
Nature

Volume: 595, P: 572-577
Protein kinase CK2 enables regulatory T cells to suppress excessive T_H2 responses in vivo

The mechanisms that control the suppressive function of T_reg cells in specific tissues are unclear. Bopp and colleagues show that T_reg cells have high expression of kinase CK2 and this is critical for their ability to suppress type 2 responses in the lungs.

Alexander Ulges
Matthias Klein
Tobias Bopp
Research19 Jan 2015
Nature Immunology

Volume: 16, P: 267-275
Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

Norbert Hilf
Sabrina Kuttruff-Coqui
Wolfgang Wick
Amendments and Corrections07 Feb 2019
Nature

Volume: 566, P: E13
Actively personalized vaccination trial for newly diagnosed glioblastoma

In a phase I trial, highly individualized peptide vaccines against unmutated tumour antigens and neoepitopes elicited sustained responses in CD8⁺ and CD4⁺ T cells, respectively, in patients with newly diagnosed glioblastoma.

Norbert Hilf
Sabrina Kuttruff-Coqui
Wolfgang Wick
Research19 Dec 2018
Nature

Volume: 565, P: 240-245