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Showing 1–3 of 3 results
Advanced filters: Author: Alexander Wepf Clear advanced filters

  • Absolute quantitative information about the stoichiometry of protein complex components can be obtained with a modified affinity purification–mass spectrometry method, as demonstrated for the human protein phosphatase 2A network.

    • Alexander Wepf
    • Timo Glatter
    • Matthias Gstaiger
    Research
    Nature Methods
    Volume: 6, P: 203-205

  • How the immune responses induced by SARS-CoV-2 and human coronavirus (hCoV) crosstalk is still unclear. Here the authors profile the humoral responses of prepandemic and SARS-CoV-2-infected donors to find that higher hCoV antibody titers are associated with SARS-CoV-2 negativity, and with reduced hospitalization in SARS-CoV-2 positive patients.

    • Irene A. Abela
    • Chloé Pasin
    • Alexandra Trkola
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-18

  • In addition to their role in apoptosis, caspases are also involved in mediating non-apoptotic events. Here the authors show that the Drosophilamyosin family member CRINKLED and its mammalian counterpart act as substrate adaptor that facilitate caspase-mediated cleavage and localised kinase activity.

    • Mariam H. Orme
    • Gianmaria Liccardi
    • Pascal Meier
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12