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Advanced filters: Author: Alexandra Bernardo-Colón Clear advanced filters

H105A peptide eye drops promote photoreceptor survival in murine and human models of retinal degeneration

Bernardo-Colón et al. evaluate small peptides derived from the neurotrophic region of pigment epithelium-derived factor (PEDF) as potential therapeutics for retinitis pigmentosa using mouse models and human retinal organoids. A significant delay in photoreceptor death with eye drop or gene therapy delivery is seen.

Alexandra Bernardo-Colón
Andrea Bighinati
S. Patricia Becerra
ResearchOpen Access21 Mar 2025
Communications Medicine

Volume: 5, P: 1-16
Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma

Chloe N. Thomas
Alexandra Bernardo-Colón
Zubair Ahmed
ResearchOpen Access19 Aug 2021
Scientific Reports

Volume: 11, P: 1-15
Antioxidants prevent inflammation and preserve the optic projection and visual function in experimental neurotrauma

Alexandra Bernardo-Colón
Victoria Vest
Tonia S. Rex
ResearchOpen Access26 Oct 2018
Cell Death & Disease

Volume: 9, P: 1-13

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