Alexandra Murschhauser et al. present a high-throughput microscopy method for the analysis of single-cell longitudinal data using fluorescent markers. They apply the method to cancer cell lines exposed to cytotoxic nanoparticles and find that 58 nm PS-NH2 nanoparticles induce a lysosomal pathway and, at high doses, lead to cell death via a mitochondrial pathway.
- Alexandra Murschhauser
- Peter J. F. Röttgermann
- Joachim O. Rädler
