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Showing 1–5 of 5 results
Advanced filters: Author: Alfred Fillol-Salom Clear advanced filters

  • During the transition from lysogeny (a stable association between a phage and its bacterial host) to the lytic cycle, prophage excision can be followed or preceded by DNA replication and packaging. Here, the authors show that prophage excision is delayed in Salmonella phage P22, thus allowing the packaging and transfer of large fragments of host DNA via lateral transduction.

    • Alfred Fillol-Salom
    • Rodrigo Bacigalupe
    • José R. Penadés
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Bacterial immune systems can recognize phage structural components to activate diverse antiviral responses. Here, the authors identify a family of bacterial immune systems, encoded in prophages and other mobile genetic elements, that protect their bacterial host population from other invading phages by blocking tail assembly.

    • Lingchen He
    • Laura Miguel-Romero
    • José R. Penadés
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • It is commonly thought that horizontal transfer of most bacterial chromosomal genes is limited, in comparison with the frequent transfer of mobile genetic elements. Humphrey et al. show that, actually, phage-mediated lateral transduction of core chromosomal genes can be more efficient than the transfer of mobile genetic elements via conjugation or generalized transduction.

    • Suzanne Humphrey
    • Alfred Fillol-Salom
    • José R. Penadés
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13

  • Little is known about the distribution, evolution and functions of the K1 capsule at a population level, despite the important role in the pathogenesis of E. coli; authors explore this through the utilisation of over 5,000 clinical isolates in population genomics studies and statistical modelling.

    • Sergio Arredondo-Alonso
    • George Blundell-Hunter
    • Alex J. McCarthy
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17