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Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage

Mutation of the nuclear envelope protein, barrier-to-autointegration factor 1 (Banf1), has previously been associated with the development of ageing associated diseases in a human progeria syndrome. Here, the authors reveal the functional link between Banf1-regulated, PARP1-directed repair of oxidative lesions.

Emma Bolderson
Joshua T. Burgess
Derek J. Richard
ResearchOpen Access03 Dec 2019
Nature Communications

Volume: 10, P: 1-12
Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images

Sajid Ali Khan
Shariq Hussain
Khalid Iqbal
ResearchOpen Access21 Mar 2019
Scientific Reports

Volume: 9, P: 1-14
COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks

Amila Suraweera et al. use a range of biochemical and in vitro cellular assays to examine the role of the COMMD4 in DNA repair. Their results suggest that COMMD4 interacts with the histone H2A-H2B during repair of double-stranded DNA breaks, thereby maintaining genomic stability by regulating chromatin structure.

Amila Suraweera
Neha S. Gandhi
Derek J. Richard
ResearchOpen Access19 Apr 2021
Communications Biology

Volume: 4, P: 1-11
hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage

Didier Boucher
Ruvini Kariawasam
Derek J. Richard
ResearchOpen Access12 Oct 2021
Scientific Reports

Volume: 11, P: 1-12

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Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage

Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks

hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage

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