Nature Search

Publisher Correction: High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy

Jeffrey Demas
Jason Manley
Alipasha Vaziri
Amendments and Corrections08 Nov 2021
Nature Methods

Volume: 18, P: 1552
Author Correction: High-speed volumetric imaging of neuronal activity in freely moving rodents

Oliver Skocek
Tobias Nöbauer
Alipasha Vaziri
Amendments and Corrections21 May 2018
Nature Methods

Volume: 15, P: 469
Confined activation and subdiffractive localization enables whole-cell PALM with genetically expressed probes

Confined photoactivation of photoactivatable mCherry using two-photon illumination with line-scanning temporal focusing in combination with three-dimensional localization algorithms allows three-dimensional super-resolution microscopy of cellular features at <50 nm lateral and <100 nm axial resolution and depths greater than 8 μm.

Andrew G York
Alireza Ghitani
Hari Shroff
Research13 Feb 2011
Nature Methods

Volume: 8, P: 327-333
High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy

Light beads microscopy is a two-photon microscopy approach that allows high-speed volumetric imaging of neuronal activity at the mesoscale.

Jeffrey Demas
Jason Manley
Alipasha Vaziri
Research30 Aug 2021
Nature Methods

Volume: 18, P: 1103-1111
A miniaturized mesoscope for the large-scale single-neuron-resolved imaging of neuronal activity in freely behaving mice

An optimized head-mounted fluorescent mesoscope enables large-scale calcium imaging at single-neuron resolution in freely moving mice, facilitating neurobehavioural studies during social interactions and fear-conditioning experiments.

Yuanlong Zhang
Lekang Yuan
Alipasha Vaziri
Research20 Jun 2024
Nature Biomedical Engineering

Volume: 8, P: 754-774
Mesoscale volumetric light-field (MesoLF) imaging of neuroactivity across cortical areas at 18 Hz

Light-field microscopy is extended to mesoscale fields of view, allowing calcium imaging of thousands of neurons at a high frame rate and high spatial resolution.

Tobias Nöbauer
Yuanlong Zhang
Alipasha Vaziri
Research23 Feb 2023
Nature Methods

Volume: 20, P: 600-609
Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy

This paper reports the use of light-field microscopy for fast, large-scale imaging of neuronal activity in vivo. It is applied to image the entire animal in the worm and the whole brain in zebrafish.

Robert Prevedel
Young-Gyu Yoon
Alipasha Vaziri
Research18 May 2014
Nature Methods

Volume: 11, P: 727-730
Entanglement of the orbital angular momentum states of photons

Alois Mair
Alipasha Vaziri
Anton Zeilinger
Research19 Jul 2001
Nature

Volume: 412, P: 313-316
The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo

The Cousa objective is an ultra-long working distance air objective optimized for two- and three-photon imaging. Bypassing challenges caused by water immersion and short working distances, the Cousa enables and improves imaging of diverse specimens.

Che-Hang Yu
Yiyi Yu
Spencer LaVere Smith
ResearchOpen Access21 Dec 2023
Nature Methods

Volume: 21, P: 132-141
Direct detection of a single photon by humans

The detection limit of human vision has remained unclear. Using a quantum light source capable of generating single-photon states of light, authors here report that humans can perceive a single photon incidence on the eye with a probability above chance.

Jonathan N. Tinsley
Maxim I. Molodtsov
Alipasha Vaziri
ResearchOpen Access19 Jul 2016
Nature Communications

Volume: 7, P: 1-9
Video rate volumetric Ca²⁺ imaging across cortex using seeded iterative demixing (SID) microscopy

The seeded iterative demixing strategy, when used in combination with light-field microscopy, enables calcium imaging at single-neuron resolution in the mouse brain at high volumetric imaging rates and depths of up to 380 μm.

Tobias Nöbauer
Oliver Skocek
Alipasha Vaziri
Research26 Jun 2017
Nature Methods

Volume: 14, P: 811-818
Volatile working memory representations crystallize with practice

Delay- and choice-related activities that are essential for working-memory performance drift during learning and stabilize only after several days of expert performance.

Arash Bellafard
Ghazal Namvar
Peyman Golshani
ResearchOpen Access15 May 2024
Nature

Volume: 629, P: 1109-1117
Fast volumetric calcium imaging across multiple cortical layers using sculpted light

Two-photon scanning microscopy is inherently slow and thus limits volumetric calcium imaging. Prevedel et al. achieve increased volumetric imaging speed by tailoring the excitation volume via light sculpting.

Robert Prevedel
Aart J Verhoef
Alipasha Vaziri
Research31 Oct 2016
Nature Methods

Volume: 13, P: 1021-1028
Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light

This work describes wide-field temporal focusing, a two-photon volumetric imaging technique based on light sculpting that enables functional imaging of the majority of neurons in the head ganglia of C. elegans with high temporal and spatial resolution.

Tina Schrödel
Robert Prevedel
Alipasha Vaziri
Research08 Sept 2013
Nature Methods

Volume: 10, P: 1013-1020
Network mechanisms of theta related neuronal activity in hippocampal CA1 pyramidal neurons

The authors studied hippocampal networks in mouse slices in vitro and found that theta-related place-cell activity in the hippocampus is generated through an interaction between a phasic dendritic excitation and a phasic perisomatic shunting inhibition mediated by interneurons.

Attila Losonczy
Boris V Zemelman
Jeffrey C Magee
Research18 Jul 2010
Nature Neuroscience

Volume: 13, P: 967-972
High-speed volumetric imaging of neuronal activity in freely moving rodents

A miniature light-field microscope in combination with a signal-extraction approach enables high-speed volumetric calcium imaging in freely moving mice.

Oliver Skocek
Tobias Nöbauer
Alipasha Vaziri
Research07 May 2018
Nature Methods

Volume: 15, P: 429-432
Wapl is an essential regulator of chromatin structure and chromosome segregation

Depletion of the cohesin-associated protein Wapl in mice is shown to increase the residence time of cohesin on DNA, which leads to clustering of cohesin in axial structures, and causes chromatin condensation in interphase chromosomes; the findings suggest that cohesin could have an architectural role in interphase chromosome organization.

Antonio Tedeschi
Gordana Wutz
Jan-Michael Peters
Research25 Aug 2013
Nature

Volume: 501, P: 564-568

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Publisher Correction: High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy

Author Correction: High-speed volumetric imaging of neuronal activity in freely moving rodents

Confined activation and subdiffractive localization enables whole-cell PALM with genetically expressed probes

High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy

A miniaturized mesoscope for the large-scale single-neuron-resolved imaging of neuronal activity in freely behaving mice

Mesoscale volumetric light-field (MesoLF) imaging of neuroactivity across cortical areas at 18 Hz

Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy

Entanglement of the orbital angular momentum states of photons

The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo

Direct detection of a single photon by humans

Video rate volumetric Ca²⁺ imaging across cortex using seeded iterative demixing (SID) microscopy

Volatile working memory representations crystallize with practice

Fast volumetric calcium imaging across multiple cortical layers using sculpted light

Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light

Network mechanisms of theta related neuronal activity in hippocampal CA1 pyramidal neurons

High-speed volumetric imaging of neuronal activity in freely moving rodents

Wapl is an essential regulator of chromatin structure and chromosome segregation

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