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Showing 1–5 of 5 results
Advanced filters: Author: Alisa H. Isaac Clear advanced filters

  • A remora-inspired mechanical underwater adhesive device adheres securely to a range of soft substrates and maintains performance under extreme pH and moisture conditions, with potential applications in biosensing and drug delivery.

    • Ziliang Kang
    • Johanna A. Gomez
    • Giovanni Traverso
    ResearchOpen Access
    Nature
    Volume: 643, P: 1271-1280

  • Concerns over the immunogenicity of poly(ethylene glycol) (PEG) are growing, and the implications for tissue engineering are unknown. Here the authors evaluate the impact of anti-PEG antibodies and PEG immunogenicity on the efficacy of a PEG hydrogel-based tissue engineering therapy.

    • Alisa H. Isaac
    • Sarea Y. Recalde Phillips
    • Daniel L. Alge
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15

  • Treatment with the oncolytic herpes virus CAN-3110 is associated with improved survival responses in patients with recurrent glioblastoma, particularly in individuals who are seropositive for HSV1.

    • Alexander L. Ling
    • Isaac H. Solomon
    • E. Antonio Chiocca
    ResearchOpen Access
    Nature
    Volume: 623, P: 157-166

  • Meta-analyses in up to 1.3 million individuals identify 87 rare-variant associations with blood pressure traits. On average, rare variants exhibit effects ~8 times larger than the mean effects of common variants and implicate candidate causal genes at associated regions.

    • Praveen Surendran
    • Elena V. Feofanova
    • Joanna M. M. Howson
    Research
    Nature Genetics
    Volume: 52, P: 1314-1332