The orphan ligand Dilp8 has been shown to coordinate growth and developmental timing in Drosophila. Here, using Gal4 drivers and CRISPR/Cas9 approaches, Garelli et al.identify a role for relaxin-like receptor Lgr3 in regulating the Dilp8 developmental delay pathway.
- Andres Garelli
- Fabiana Heredia
- Alisson M. Gontijo