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Showing 1–7 of 7 results
Advanced filters: Author: Allan Herbison Clear advanced filters

  • The mechanisms controlling reproductive hormone secretion are unclear. Here the authors show that noradrenergic inputs to kisspeptin neurons are able to control pulsatile hormone release in a sex- and gonadal steroid-dependent manner.

    • Szilvia Vas
    • Paul G. Morris
    • Allan E. Herbison
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15

  • An elaborate neural network integrating many internal homeostatic and external signals governs the onset of puberty and subsequent fertility. Here, Allan Herbison provides an update on the morphology and function of the gonadotropin-releasing hormone neurons, focusing on their role in the onset of puberty and fertility.

    • Allan E. Herbison
    Reviews
    Nature Reviews Endocrinology
    Volume: 12, P: 452-466

  • Mate preference and copulatory behavior in female rodents are coordinated with the ovulation cycles of the animal. This study shows that hypothalamic kisspeptin neurons control both mate choice and copulation, and therefore, that sexual behavior and ovulation may be synchronized by the same neuropeptide.

    • Vincent Hellier
    • Olivier Brock
    • Julie Bakker
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12

  • The kisspeptin receptor GPR54 is implicated in the maintenance of mammalian fertility. Kirilov et al.study GPR54 mutant mice and identify a subset of neurons in the brain expressing gonadotropin-releasing hormone as the critical site for kisspeptin action.

    • Milen Kirilov
    • Jenny Clarkson
    • Allan E. Herbison
    Research
    Nature Communications
    Volume: 4, P: 1-11

  • Estrogen secreted by the ovary controls how the brain drives pulsatile reproductive hormone secretion. The authors show that in mice, estrogen receptor alpha within a specific population of hypothalamic kisspeptin neurons is the principal pathway through which estrogen brings about this classic negative feedback pathway common to all mammals.

    • H. James McQuillan
    • Jenny Clarkson
    • Allan E. Herbison
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • Anti-Müllerian hormone (AMH) plays a role in sexual differentiation and gonadal function, but extra-gonadal effects of AMH are not known. Here Cimino et al. show that AMH activates a subset of gonadotrophin-releasing hormone (GnRH)-releasing neurons, contributing to luteinizing hormone secretion from the pituitary gland.

    • Irene Cimino
    • Filippo Casoni
    • Paolo Giacobini
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12