The six major apolipoprotein B (apoB) dyslipoproteinemias can be specifically identified according to a diagnostic algorithm based on levels of total cholesterol, triglycerides and apoB. The authors of this Review delineate the characteristic apoB phenotype of the major apoB dyslipoproteinemias and their underlying pathophysiology and provide a treatment plan which aims at a reduction of atherogenic apoB particles—in particular, remnants and LDL particles—rather than plasma lipid levels.
- Allan Sniderman
- Patrick Couture
- Jacqueline de Graaf
