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Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques

A genetic method to block immune rejection of allogeneic cells is validated in monkeys.

Xiaomeng Hu
Kathy White
Sonja Schrepfer
ResearchOpen Access08 May 2023
Nature Biotechnology

Volume: 42, P: 413-423
Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy

SARS-CoV-2-specific antibodies and memory B cells are significantly reduced, but CD4⁺ and CD8⁺ T cells are robustly activated, in patients with multiple sclerosis on anti-CD20 monotherapy versus healthy controls after BNT162b2 or mRNA-1273 mRNA vaccination.

Sokratis A. Apostolidis
Mihir Kakara
Amit Bar-Or
ResearchOpen Access14 Sept 2021
Nature Medicine

Volume: 27, P: 1990-2001
Neptune: an environment for the delivery of genomic medicine

Venner Eric
Victoria Yi
Hana Zouk
Research13 Jul 2021
Genetics in Medicine

Volume: 23, P: 1838-1846

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