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Advanced filters: Author: Amanda M. Perozzo Clear advanced filters

GluA2-containing AMPA receptors form a continuum of Ca²⁺-permeable channels

GluA2-containing AMPA receptors (AMPARs) are not Ca²⁺ impermeable, and their ability to transport Ca²⁺ is shaped by the subunit composition of AMPAR tetramers as well as the orientation of transmembrane AMPAR regulatory proteins and cornichon auxiliary subunits.

Federico Miguez-Cabello
Xin-tong Wang
Derek Bowie
Research19 Mar 2025
Nature

Volume: 641, P: 537-544
GSG1L-containing AMPA receptor complexes are defined by their spatiotemporal expression, native interactome and allosteric sites

TARPs and GSG1L are evolutionarily- and structurally-related AMPA receptor auxiliary subunits that differ in function through unresolved mechanisms. Here, the authors provide insight into the spatiotemporal expression, composition, and functionality of GSG1L-containing protein complexes.

Amanda M. Perozzo
Jochen Schwenk
Derek Bowie
ResearchOpen Access26 Oct 2023
Nature Communications

Volume: 14, P: 1-15
Survival Motor Neuron Protein is Released from Cells in Exosomes: A Potential Biomarker for Spinal Muscular Atrophy

Leslie A. Nash
Emily R. McFall
Robin J. Parks
ResearchOpen Access24 Oct 2017
Scientific Reports

Volume: 7, P: 1-15

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