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Showing 1–3 of 3 results
Advanced filters: Author: Amber A. W. A. van der Heijden Clear advanced filters

  • There is an urgent need for biomarkers for type 2 diabetes progression that provide a deeper understanding of the disease process. Here, the authors identify biomarkers in three molecular classes, replicate them in other cohorts and explore top protein biomarkers in detail in functional studies.

    • Roderick C. Slieker
    • Louise A. Donnelly
    • Guy A. Rutter
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • Ewan Pearson, Kathleen Giacomini and the Metformin Genetics Consortium perform a genome-wide association study for glycemic response to the antidiabetic drug metformin. They find an intronic allele of the GLUT2 glucose transporter gene that associates with greater metformin action, an effect that is more pronounced in obese individuals.

    • Kaixin Zhou
    • Sook Wah Yee
    • Ewan R Pearson
    Research
    Nature Genetics
    Volume: 48, P: 1055-1059