Advances in the fields of genetics and gene-expression profiling and the advent of microarray technology have revolutionized the concept of patient tailored treatment. Before microarrays qualify as a useful clinical tool, however, they must demonstrate reliability and reproducibility. Limitations of microarray technology include sample acquisition and methods of biostatistical analysis required to analyze the enormous quantities of data obtained. Abdullah-Sayaniet al.overview the current status of microarray technology in clinical practice and propose how advances in this technology will help eliminate some of these limitations and improve patient management.
- Ambreen Abdullah-Sayani
- Jolien M Bueno-de-Mesquita
- Marc J van de Vijver
